Usually individuals with Rheses negative (RH-) bloodtype who have an abortion or miscarriage after 12 weeks or delivery are advised to have an injection of anti-D globulin. If the fetus has a positive blood-type and it is exchanged with the woman, the woman's body can produce antibodies that can potentially affect another fetus if she decides to have another baby.
However, research indicates that early medical abortion (in the first 12 weeks) and first trimester spontaneous miscarriages have no or very little exchange in blood between the pregnant woman and the fetus, and that the pregnant individual does not make a significant amount of antibodies that could affect the next fetus. Therefore, anti-D globulin is not prescribed in these cases.
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